Seeking a one-shot solution to anthrax threat
Emergency Management Alert, October 16, 2007
The effort to develop a new anthrax vaccine continues. The Public Library of Science posted these research results Oct. 5. Referring to the fact that the current vaccine requires multiple injections followed by annual boosters, the authors said that they sought to create a "well-characterized vaccine" that induces immunity after a single injection: "We developed a reagent that combines the functions of an anthrax antitoxin and vaccine in a single compound."
The Department of Health and Human Services (HHS) has been trying to acquire a vaccine that would require fewer doses and cause fewer side effects. Right now it is stockpiling Anthrax Vaccine Adsorbed (AVA), the only anthrax vaccine licensed in the United States. AVA, developed in the 1950s, requires six doses, with an annual booster recommended thereafter. On Sept. 26 HHS announced the purchase of 18.75 million doses of BioThrax AVA from Emergent Biodefense Operations of Lansing, Mich., at a total of $448 million.
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