Safety

Aspirin therapy before surgery is "balancing act"

Ambulatory Safety Monitor, May 5, 2005

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Researchers have found that patients taking aspirin on a regular bases for heart disease need to be careful not to stop taking the drug too soon or too late before elective surgery, according to Reuters.

The research, published in the Journal of the American College of Surgeons, suggests patients stop taking aspirin five days before surgery to ensure that their blood clots normally on the day of the procedure.

Stopping too early could lead to an increase in risk for clot-related problems. Stopping too late could lead to bleeding problems during the procedure.

Based on data from 38 subjects tested for 14 days using aspirin and inactive placebo,"we believe that aspirin therapy should be discontinued 5 days before elective surgery and the operation planned for the sixth day after treatment cessation," the authors conclude, according to Reuters. "This should allow physicians and surgeons to minimize the risks of stopping aspirin without increasing the risk of excessive perioperative bleeding."



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