Infection Control

One H1N1 shot for older children, two for younger

Infection Control Weekly Monitor, September 23, 2009

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Early test results of the H1N1 vaccine in children point toward just one vaccination rather than two, according to the National Institute of Allergy and Infectious Diseases (NIAID).

Analysis of blood samples from a small group of trial participants shows that a single 15-microgram dose of the H1N1 vaccine generates an immune response that should protect against the H1N1 virus in the majority of children ages 10-17, according to the NIAID.

Researchers saw a strong immune response in 76% of participants. In children ages 3-9 years old, a strong immune response was seen in just 36% with one dose of the vaccine, leading federal officials to speculate that younger children will need two shots a few weeks apart.



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