Infection Control

CDC guidance for CRKP

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Carbapenem-resistant Enterobacteriaceae (CRE) or carbapenemase-producing Enterobacteriaceae is quickly emerging as a more virulent and dangerous MDRO, according to a December article in the Journal of the American Medical Association (JAMA). In the United States carbapenem-resistant Klebsiella pneumoniae (CRKP) is the most common form of CRE, and infections have led to high rates of morbidity and mortality.

An article published in JAMA on May 20, points out some of the dangers of this new infection, and offers recommendations for treating and mitigating the spread of CRKP.

JAMA notes that recent reports have demonstrated that healthcare facilities can track CRKP through broth-based culture techniques, and also through in-house prepared molecular techniques and a commercial chromogenic agar. The Food and Drug Administration has not yet approved the latter two. In the meantime, the CDC and the Healthcare Infection Control Practices Advisory Committee (HICPAC) has developed guidance for acute-care facilities.

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