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Researchers: Glucose a MRSA enabler

Infection Control Monitor, September 2, 2005

Methicillin-resistant Staphylococcus aureus (MRSA), one of the most serious hospital-acquired infections, poses a greater risk to critically ill patients with glucose in their airways, according to a study published recently in the journal Thorax.

The study included 98 patients in intensive care who required mechanical assistance with their breathing for longer than 48 hours.

Researchers found glucose in the bronchial aspirates of 58 of 98 patients. Blood glucose levels in those patients tended to be higher as well. Researchers tested the aspirates of 87 patients for harmful bacteria. Aspirates containing glucose were twice as likely to contain MRSA as those with no measurable glucose levels.

Staphylococcus aureus uses glucose as fuel during a period rapid growth, researchers say. Glucose may also interfere the body's immune response in the airway.

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